Karlee: Hyper-Efficient Operative Build (2025 Meta)
This build focuses on leveraging Karlee's innate abilities for rapid objective completion, unparalleled support item deployment, and enhanced team awareness, making her an indispensable asset in high-difficulty scenarios anticipated in 2025.
Core Philosophy: Speed & Support Supremacy
The 2025 meta for Karlee emphasizes maximizing her Use Speed for objectives and quick item deployment, coupled with cards that bolster team utility and survivability. This build transforms Karlee into a crucial objective specialist and support linchpin.

Key Card Synergies:
- Core Use Speed & Awareness:
- Screwdriver / Headband Magnifier (or future high-tier equivalents): Non-negotiable for maximizing interaction speed. In a 2025 meta, aim for the highest Use Speed with the least detrimental side effects.
- Utility Scavenger / Support Scavenger: Synergizes perfectly with Karlee's innate item highlighting, ensuring a steady supply of crucial tools and medical items for the team.
- Enhanced Team Support:
- Experienced EMT / Combat Medic: Faster revives and more effective healing are amplified by Karlee's Use Speed. Trauma mitigation becomes highly efficient.
- Surplus Pouches / Tool Belts: Capitalizes on the team's +1 Quick Slot from Karlee and her item-finding prowess, allowing her to carry an even wider array of essential gear like defibrillators or pipe bombs.
- Amped Up / Needs of the Many (or similar team buff): Cards that provide sustained team benefits upon objective completion or via passive effects. Karlee's role often keeps her near the team or completing objectives, maximizing these benefits.
- Mobility & Defense:
- Run Like Hell / Cross Trainers: Essential for navigating to objectives quickly, kiting dangerous mutations, and repositioning during hectic fights. Speed is key to survival and objective focus.
- Down In Front!: A staple for objective-focused play, preventing friendly fire incidents during crucial interactions (e.g., defusing, repairing) or when holding chokepoints.
- Shredder / Marked for Death: While not the primary damage dealer, contributing to special Ridden takedowns is vital. These cards enhance team damage output on key targets Karlee can help identify or engage.
Weapon Prioritization:
- Primary Weapon: Assault Rifles (e.g., M4 Carbine, SCAR) or SMGs (e.g., UMP45, Vector) with attachments prioritizing stumble power, reload speed, and accuracy. These offer versatility for both clearing common Ridden and assisting with specials.
- Secondary Weapon: High-damage pistols (e.g., Desert Eagle, Magnum) or reliable sidearms (e.g., Glock Auto) for emergencies or when primary ammo is scarce.
Playstyle & Team Role:
Objective Specialist: Karlee should always be the primary interactor with objectives due to her superior Use Speed. This includes defusing bombs, starting generators, opening doors, and interacting with mission-critical items.
Item & Hazard Spotter: Continuously use her passive ability to highlight items, hazards, and special Ridden. Communicate these findings clearly to the team to improve situational awareness and resource management.
Support Anchor: Utilize enhanced Use Speed for rapid deployment of support items like First Aid Kits, defibrillators, or Tool Kits. The extra quick slot should always carry a high-impact item.
Strategic Positioning: Stay mobile, using speed to reach objectives safely and evade threats. During defensive phases, position yourself to cover interactable points while supporting teammates.
This 2025 Karlee build focuses on a proactive, objective-driven playstyle, significantly reducing mission times and increasing team survivability through efficient support and superior awareness.